Thrombin-Receptor Antagonist Vorapaxar in Acute Coronary Syndromes
Author(s) -
Pierluigi Tricoci,
Zhen Huang,
Claes Held,
David J. Moliterno,
Paul W. Armstrong,
Frans Van de Werf,
Harvey D. White,
Philip E. Aylward,
Lars Wallentin,
Edmond Chen,
Yuliya Lokhnygina,
Jinglan Pei,
Sergio Leonardi,
Tyrus Rorick,
A. Kilian,
Lisa Jennings,
Giuseppe Ambrosio,
Christoph Bode,
Ángel Cequier,
Jan H. Cornel,
Rafael Díaz,
Aycan Fahri Erkan,
Kurt Huber,
Michael Hudson,
Lixin Jiang,
J. Wouter Jukema,
Basil S. Lewis,
A. Michael Lincoff,
Gilles Montalescot,
José Carlos Nicolau,
Hisao Ogawa,
Matthias Pfisterer,
Juan Carlos Prieto,
Witold Rużyłło,
Peter Sinnaeve,
Robert F. Storey,
Marco Valgimigli,
David J. Whellan,
Petr Widimský,
John Strony,
Robert A. Harrington,
Kenneth W. Mahaffey
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1109719
Subject(s) - medicine , thrombin , antagonist , receptor antagonist , pharmacology , thrombin receptor , receptor , platelet activation , platelet
Vorapaxar is a new oral protease-activated-receptor 1 (PAR-1) antagonist that inhibits thrombin-induced platelet activation.
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