Wnt Signaling and Dupuytren's Disease | Zendy

Guido H. Dolmans | Zendy; Paul M. N. Werker | Zendy; Hans Christian Hennies | Zendy; Dominic Furniss | Zendy; Eleonora A. Festen | Zendy; Lude Franke | Zendy; Kerstin Becker | Zendy; Pieter van der Vlies | Zendy; Bruce H. R. Wolffenbuttel | Zendy; Sigrid Tinschert | Zendy; Mohammad R. Toliat | Zendy; Michael Nothnagel | Zendy; André Franke | Zendy; Norman Klopp | Zendy; H. E. Wichmann | Zendy; Peter Nürnberg | Zendy; Henk Giele | Zendy; Roel A. Ophoff | Zendy; Cisca Wijmenga | Zendy

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Wnt Signaling and Dupuytren's Disease

Author(s) -

Guido H. Dolmans,

Paul M. N. Werker,

Hans Christian Hennies,

Dominic Furniss,

Eleonora A. Festen,

Lude Franke,

Kerstin Becker,

Pieter van der Vlies,

Bruce H. R. Wolffenbuttel,

Sigrid Tinschert,

Mohammad R. Toliat,

Michael Nothnagel,

André Franke,

Norman Klopp,

H. E. Wichmann,

Peter Nürnberg,

Henk Giele,

Roel A. Ophoff,

Cisca Wijmenga

Publication year - 2011

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1101029

Subject(s) - odds ratio , single nucleotide polymorphism , medicine , case control study , genetics , dupuytren's contracture , disease , genome wide association study , bioinformatics , genotype , biology , gene , surgery , contracture

Dupuytren's disease is a benign fibromatosis of the hands and fingers that leads to flexion contractures. We hypothesized that multiple genetic and environmental factors influence susceptibility to this disease and sought to identify susceptibility genes to better understand its pathogenesis.

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