Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection
Author(s) -
Ira M. Jacobson,
John G. McHutchison,
Geoffrey Dusheiko,
Adrian M. Di Bisceglie,
K. Rajender Reddy,
Natalie Bzowej,
Patrick Marcellin,
Andrew J. Muir,
Péter Ferenci,
Robert Flisiak,
Jacob George,
Mario Rizzetto,
Daniel Shouval,
Ricard Solà,
Rubén Terg,
Eric M. Yoshida,
Nathalie Adda,
Leif Bengtsson,
Abdul J. Sankoh,
Tara L. Kieffer,
Shelley George,
Robert S. Kauffman,
Stefan Zeuzem
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1012912
Subject(s) - ribavirin , telaprevir , medicine , gastroenterology , placebo , hepatitis c virus , peginterferon alfa 2a , virology , hepatitis c , virus , pathology , alternative medicine
In phase 2 trials, telaprevir, a hepatitis C virus (HCV) genotype 1 protease inhibitor, in combination with peginterferon-ribavirin, as compared with peginterferon-ribavirin alone, has shown improved efficacy, with potential for shortening the duration of treatment in a majority of patients.
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