Rivaroxaban versus Warfarin in Nonvalvular Atrial Fibrillation
Author(s) -
Manesh R. Patel,
Kenneth W. Mahaffey,
Jyotsna Garg,
Guohua Pan,
Daniel E. Singer,
Werner Hacke,
Günter Breithardt,
Jonathan L. Halperin,
Graeme J. Hankey,
Jonathan P. Piccini,
Richard C. Becker,
Christopher C. Nessel,
John F. Paolini,
Scott D. Berkowitz,
Keith A.A. Fox,
Robert M. Califf
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1009638
Subject(s) - rivaroxaban , medicine , warfarin , atrial fibrillation , hazard ratio , stroke (engine) , clinical endpoint , confidence interval , embolism , anesthesia , cardiology , randomized controlled trial , surgery , mechanical engineering , engineering
The use of warfarin reduces the rate of ischemic stroke in patients with atrial fibrillation but requires frequent monitoring and dose adjustment. Rivaroxaban, an oral factor Xa inhibitor, may provide more consistent and predictable anticoagulation than warfarin.
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