Tiotropium Bromide Step-Up Therapy for Adults with Uncontrolled Asthma
Author(s) -
Stephen P. Peters,
Susan J. Kunselman,
Nikolina Icitovic,
Wendy C. Moore,
Rodolfo M. Pascual,
Bill T. Ameredes,
Homer A. Boushey,
William J. Calhoun,
Mario Castro,
Reuben M. Cherniack,
Timothy Craig,
Loren C. Denlinger,
Linda Engle,
Emily DiMango,
John V. Fahy,
Elliot Israel,
Nizar N. Jarjour,
Shamsah Kazani,
Monica Kraft,
Stephen C. Lazarus,
Robert F. Lemanske,
Njira Lugogo,
Richard J. Martin,
Deborah A. Meyers,
Joe Ramsdell,
Christine A. Sorkness,
E. Rand Sutherland,
Stanley J. Szefler,
Stephen I. Wasserman,
Michael Walter,
Michael E. Wechsler,
Ver M. Chinchilli,
Eugene R. Bleecker
Publication year - 2010
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1008770
Subject(s) - medicine , salmeterol , tiotropium bromide , asthma , anesthesia , bronchodilator , morning , crossover study , glucocorticoid , copd , inhaler , bronchodilation , minimal clinically important difference , randomized controlled trial , placebo , lung function , lung , alternative medicine , pathology
Long-acting beta-agonist (LABA) therapy improves symptoms in patients whose asthma is poorly controlled by an inhaled glucocorticoid alone. Alternative treatments for adults with uncontrolled asthma are needed.
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