Effect of Occult Metastases on Survival in Node-Negative Breast Cancer
Author(s) -
Donald L. Weaver,
Takamaru Ashikaga,
David N. Krag,
Joan M. Skelly,
Stewart Anderson,
Seth P. Harlow,
Thomas B. Julian,
Eleftherios P. Mamounas,
Norman Wolmark
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1008108
Subject(s) - medicine , occult , breast cancer , oncology , lymph node , observational study , retrospective cohort study , disease , cancer , sentinel lymph node , sentinel node , randomized controlled trial , pathology , alternative medicine
Retrospective and observational analyses suggest that occult lymph-node metastases are an important prognostic factor for disease recurrence or survival among patients with breast cancer. Prospective data on clinical outcomes from randomized trials according to sentinel-node involvement have been lacking.
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