Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis | Zendy

Amit Khera | Zendy; Marina Cuchel | Zendy; Margarita de la Llera-Moya | Zendy; Amrith Rodrigues | Zendy; Megan F. Burke | Zendy; Kashif Jafri | Zendy; Benjamin French | Zendy; Julie A. Phillips | Zendy; Megan Mucksavage | Zendy; Robert L. Wilensky | Zendy; Emile R. Mohler | Zendy; George H. Rothblat | Zendy; Daniel J. Rader | Zendy

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Cholesterol Efflux Capacity, High-Density Lipoprotein Function, and Atherosclerosis

Author(s) -

Amit Khera,

Marina Cuchel,

Margarita de la Llera-Moya,

Amrith Rodrigues,

Megan F. Burke,

Kashif Jafri,

Benjamin French,

Julie A. Phillips,

Megan Mucksavage,

Robert L. Wilensky,

Emile R. Mohler,

George H. Rothblat,

Daniel J. Rader

Publication year - 2011

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1001689

Subject(s) - medicine , odds ratio , cholesterol , efflux , apolipoprotein b , endocrinology , high density lipoprotein , coronary artery disease , lipoprotein , confidence interval , cardiology , biology , biochemistry

High-density lipoprotein (HDL) may provide cardiovascular protection by promoting reverse cholesterol transport from macrophages. We hypothesized that the capacity of HDL to accept cholesterol from macrophages would serve as a predictor of atherosclerotic burden.

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