Antiretroviral Treatment for Children with Peripartum Nevirapine Exposure | Zendy

Paul Palumbo | Zendy; Jane C. Lindsey | Zendy; Michael D. Hughes | Zendy; Mark F. Cotton | Zendy; Raziya Bobat | Zendy; Tammy Meyers | Zendy; Mutsa BwakuraDangarembizi | Zendy; H. Benjamin | Zendy; Philippa Musoke | Zendy; Portia Kamthunzi | Zendy; Werner Schimana | Zendy; Lynette Purdue | Zendy; Susan H. Eshleman | Zendy; Elaine J. Abrams | Zendy; Linda Millar | Zendy; Elizabeth Petzold | Zendy; Lynne Mofenson | Zendy; Patrick JeanPhilippe | Zendy; Avy Violari | Zendy

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Antiretroviral Treatment for Children with Peripartum Nevirapine Exposure

Author(s) -

Paul Palumbo,

Jane C. Lindsey,

Michael D. Hughes,

Mark F. Cotton,

Raziya Bobat,

Tammy Meyers,

Mutsa BwakuraDangarembizi,

H. Benjamin,

Philippa Musoke,

Portia Kamthunzi,

Werner Schimana,

Lynette Purdue,

Susan H. Eshleman,

Elaine J. Abrams,

Linda Millar,

Elizabeth Petzold,

Lynne Mofenson,

Patrick JeanPhilippe,

Avy Violari

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1000931

Subject(s) - nevirapine , medicine , regimen , antiretroviral treatment , human immunodeficiency virus (hiv) , transmission (telecommunications) , virology , pregnancy , pediatrics , antiretroviral therapy , immunology , viral load , biology , electrical engineering , genetics , engineering

Single-dose nevirapine is the cornerstone of the regimen for prevention of mother-to-child transmission of human immunodeficiency virus (HIV) in resource-limited settings, but nevirapine frequently selects for resistant virus in mothers and children who become infected despite prophylaxis. The optimal antiretroviral treatment strategy for children who have had prior exposure to single-dose nevirapine is unknown.

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