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Gentamicin–Collagen Sponge for Infection Prophylaxis in Colorectal Surgery
Author(s) -
Elliott BennettGuerrero,
Theodore N. Pappas,
Walter A. Koltun,
James W. Fleshman,
Min Lin,
Jyotsna Garg,
Daniel B. Mark,
Jorge Marcet,
Feza H. Remzi,
Virgilio George,
Kerstin Newland,
G. Ralph Corey
Publication year - 2010
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa1000837
Subject(s) - medicine , gentamicin , antibiotics , surgery , antibiotic prophylaxis , colorectal surgery , surgical site infection , abdominal surgery , microbiology and biotechnology , biology
Despite the routine use of prophylactic systemic antibiotics, surgical-site infection continues to be associated with significant morbidity and cost after colorectal surgery. The gentamicin-collagen sponge, an implantable topical antibiotic agent, is approved for surgical implantation in 54 countries. Since 1985, more than 1 million patients have been treated with the sponges.

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