Reduced Treatment Intensity in Patients with Early-Stage Hodgkin's Lymphoma | Zendy

Andreas Engert | Zendy; Annette Plütschow | Zendy; Hans Theodor Eich | Zendy; Andreas Lohri | Zendy; Bernd Dörken | Zendy; Peter Borchmann | Zendy; Bernhard Berger | Zendy; Richard Greil | Zendy; Kay Willborn | Zendy; Martin Wilhelm | Zendy; Jürgen Debus | Zendy; Michael J. Eble | Zendy; Martin Sökler | Zendy; Antony D. Ho | Zendy; Andreas Rank | Zendy; Arnold Ganser | Zendy; Lorenz Trümper | Zendy; Carsten Bokemeyer | Zendy; Hartmut Kirchner | Zendy; Jörg Schubert | Zendy; Zdeněk Král | Zendy; Michael Fuchs | Zendy; Hans–Konrad Müller–Hermelink | Zendy; RolfPeter Müller | Zendy; Volker Diehl | Zendy

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Reduced Treatment Intensity in Patients with Early-Stage Hodgkin's Lymphoma

Author(s) -

Andreas Engert,

Annette Plütschow,

Hans Theodor Eich,

Andreas Lohri,

Bernd Dörken,

Peter Borchmann,

Bernhard Berger,

Richard Greil,

Kay Willborn,

Martin Wilhelm,

Jürgen Debus,

Michael J. Eble,

Martin Sökler,

Antony D. Ho,

Andreas Rank,

Arnold Ganser,

Lorenz Trümper,

Carsten Bokemeyer,

Hartmut Kirchner,

Jörg Schubert,

Zdeněk Král,

Michael Fuchs,

Hans–Konrad Müller–Hermelink,

RolfPeter Müller,

Volker Diehl

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa1000067

Subject(s) - medicine , stage (stratigraphy) , regimen , lymphoma , radiation therapy , chemotherapy , oncology , hodgkin lymphoma , randomized controlled trial , intensity (physics) , paleontology , biology , physics , quantum mechanics

Whether it is possible to reduce the intensity of treatment in early (stage I or II) Hodgkin's lymphoma with a favorable prognosis remains unclear. We therefore conducted a multicenter, randomized trial comparing four treatment groups consisting of a combination chemotherapy regimen of two different intensities followed by involved-field radiation therapy at two different dose levels.

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