Peginterferon plus Adefovir versus Either Drug Alone for Hepatitis Delta
Author(s) -
Heiner Wedemeyer,
Cihan Yurdaydìn,
George Ν. Dalekos,
Andreas Erhardt,
Yılmaz Çakaloğlu,
Halil Değertekin,
Selım Gürel,
Stefan Zeuzem,
Kalliopi Zachou,
Hakan Bozkaya,
Armin Koch,
C.Thomas Bock,
Hans Peter Dienes,
Michael P. Manns
Publication year - 2011
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0912696
Subject(s) - adefovir , medicine , virology , chronic hepatitis , gastroenterology , drug , hepatitis d , virus , hepatitis b virus , pharmacology , lamivudine , hbsag
Chronic infection with hepatitis B virus and hepatitis delta virus (HDV) results in the most severe form of viral hepatitis. There is no currently approved treatment. We investigated the safety and efficacy of 48 weeks of treatment with peginterferon alfa-2a plus adefovir dipivoxil, peginterferon alfa-2a alone, and adefovir dipivoxil alone.
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