Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease | Zendy

John R. Hurst | Zendy; Jørgen Vestbo | Zendy; Antonio Anzueto | Zendy; Nicholas Locantore | Zendy; Hana Müllerová | Zendy; Ruth TalSinger | Zendy; Bruce E. Miller | Zendy; David A. Lomas | Zendy; Àlvar Agustí | Zendy; William MacNee | Zendy; Peter M.A. Calverley | Zendy; Stephen I. Rennard | Zendy; Emiel F.�M. Wouters | Zendy; Jadwiga A. Wedzicha | Zendy

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Susceptibility to Exacerbation in Chronic Obstructive Pulmonary Disease

Author(s) -

John R. Hurst,

Jørgen Vestbo,

Antonio Anzueto,

Nicholas Locantore,

Hana Müllerová,

Ruth TalSinger,

Bruce E. Miller,

David A. Lomas,

Àlvar Agustí,

William MacNee,

Peter M.A. Calverley,

Stephen I. Rennard,

Emiel F.�M. Wouters,

Jadwiga A. Wedzicha

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0909883

Subject(s) - medicine , exacerbation , copd , obstructive lung disease , stage (stratigraphy) , severity of illness , disease , cohort , cohort study , intensive care medicine , paleontology , biology

Although we know that exacerbations are key events in chronic obstructive pulmonary disease (COPD), our understanding of their frequency, determinants, and effects is incomplete. In a large observational cohort, we tested the hypothesis that there is a frequent-exacerbation phenotype of COPD that is independent of disease severity.

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