Variant ofTYRand Autoimmunity Susceptibility Loci in Generalized Vitiligo
Author(s) -
Ying Jin,
Stanca A. Birlea,
Pamela R. Fain,
Katherine Gowan,
Sheri L. Riccardi,
Paulene J. Holland,
Christina M. Mailloux,
Alexandra Sufit,
Saunie M. Hutton,
Anita AmadiMyers,
Dorothy C. Bennett,
Margaret R. Wallace,
Wayne T. McCormack,
E. Helen Kemp,
David J. Gawkrodger,
Anthony P. Weetman,
Mauro Picardo,
Giovanni Leone,
Alain Taı̈eb,
Thomas Jouary,
Khaled Ezzedine,
N. van Geel,
Jo Lambert,
Andreas Overbeck,
Richard A. Spritz
Publication year - 2010
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0908547
Subject(s) - vitiligo , single nucleotide polymorphism , depigmentation , immunology , ptpn22 , genotype , medicine , haplotype , autoimmunity , genetics , major histocompatibility complex , gene , biology , immune system
Generalized vitiligo is an autoimmune disease characterized by melanocyte loss, which results in patchy depigmentation of skin and hair, and is associated with an elevated risk of other autoimmune diseases.
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