Genetic Ancestry in Lung-Function Predictions | Zendy

Rajesh Kumar | Zendy; Max A. Seibold | Zendy; Melinda C. Aldrich | Zendy; L. Keoki Williams | Zendy; Alex P. Reiner | Zendy; Laura A. Colangelo | Zendy; Joshua Galanter | Zendy; Christopher R. Gignoux | Zendy; Donglei Hu | Zendy; Śaunak Sen | Zendy; Shweta Choudhry | Zendy; Edward L. Peterson | Zendy; José RodríguezSantana | Zendy; William Rodríguez-Cintrón | Zendy; Michael A. Nalls | Zendy; Tennille S. Leak | Zendy; Ellen S. O’Meara | Zendy; Bernd Meibohm | Zendy; Stephen B. Kritchevsky | Zendy; Rongling Li | Zendy; Tamara B. Harris | Zendy; Deborah A. Nickerson | Zendy; Myriam Fornage | Zendy; Paul Enright | Zendy; Elad Ziv | Zendy; Lewis J. Smith | Zendy; Kiang Liu | Zendy; Esteban G. Burchard | Zendy

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Genetic Ancestry in Lung-Function Predictions

Author(s) -

Rajesh Kumar,

Max A. Seibold,

Melinda C. Aldrich,

L. Keoki Williams,

Alex P. Reiner,

Laura A. Colangelo,

Joshua Galanter,

Christopher R. Gignoux,

Donglei Hu,

Śaunak Sen,

Shweta Choudhry,

Edward L. Peterson,

José RodríguezSantana,

William Rodríguez-Cintrón,

Michael A. Nalls,

Tennille S. Leak,

Ellen S. O’Meara,

Bernd Meibohm,

Stephen B. Kritchevsky,

Rongling Li,

Tamara B. Harris,

Deborah A. Nickerson,

Myriam Fornage,

Paul Enright,

Elad Ziv,

Lewis J. Smith,

Kiang Liu,

Esteban G. Burchard

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0907897

Subject(s) - medicine , genetic genealogy , cohort , asthma , lung function , vital capacity , ethnic group , pulmonary function testing , demography , covariate , regression analysis , ancestry informative marker , african american , linear regression , lung , statistics , population , single nucleotide polymorphism , environmental health , genotype , genetics , diffusing capacity , sociology , biology , anthropology , history , ethnology , mathematics , gene

Self-identified race or ethnic group is used to determine normal reference standards in the prediction of pulmonary function. We conducted a study to determine whether the genetically determined percentage of African ancestry is associated with lung function and whether its use could improve predictions of lung function among persons who identified themselves as African American.

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