A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults | Zendy

Neil French | Zendy; Stephen B. Gordon | Zendy; Thandie S. Mwalukomo | Zendy; Sarah White | Zendy; Gershom Mwafulirwa | Zendy; Herbert Longwe | Zendy; Martin Mwaiponya | Zendy; Eduard E. Zijlstra | Zendy; Malcolm E. Molyneux | Zendy; Charles F. Gilks | Zendy

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A Trial of a 7-Valent Pneumococcal Conjugate Vaccine in HIV-Infected Adults

Author(s) -

Neil French,

Stephen B. Gordon,

Thandie S. Mwalukomo,

Sarah White,

Gershom Mwafulirwa,

Herbert Longwe,

Martin Mwaiponya,

Eduard E. Zijlstra,

Malcolm E. Molyneux,

Charles F. Gilks

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0903029

Subject(s) - medicine , serotype , vaccination , pneumococcal conjugate vaccine , pneumococcal polysaccharide vaccine , streptococcus pneumoniae , hazard ratio , placebo , pneumococcal vaccine , adverse effect , pneumococcal infections , immunology , vaccine trial , confidence interval , pneumococcal disease , microbiology and biotechnology , biology , antibiotics , alternative medicine , pathology

Streptococcus pneumoniae is a leading and serious coinfection in adults with human immunodeficiency virus (HIV) infection, particularly in Africa. Prevention of this disease by vaccination with the current 23-valent polysaccharide vaccine is suboptimal. Protein conjugate vaccines offer a further option for protection, but data on their clinical efficacy in adults are needed.

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