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Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease
Author(s) -
Robert Clarke,
John F. Peden,
Jemma C. Hopewell,
Theodosios Kyriakou,
Anuj Goel,
Simon Heath,
Sarah Parish,
Simona Barlera,
Maria Grazia Franzosi,
Stephan Rust,
Derrick Bennett,
Angela Silveira,
Anders Mälarstig,
Fiona R. Green,
Mark Lathrop,
Bruna Gigante,
Karin Leander,
Ulf dé Fairé,
Udo Seedorf,
Anders Hamsten,
Rory Collins,
Hugh Watkins,
Martin Farrall
Publication year - 2009
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0902604
Subject(s) - lipoprotein(a) , medicine , coronary artery disease , lipoprotein , risk factor , disease , genetic variants , atherosclerotic cardiovascular disease , cardiology , genetics , cholesterol , gene , genotype , biology
An increased level of Lp(a) lipoprotein has been identified as a risk factor for coronary artery disease that is highly heritable. The genetic determinants of the Lp(a) lipoprotein level and their relevance for the risk of coronary disease are incompletely understood.

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