Open AccessStrict Blood-Pressure Control and Progression of Renal Failure in Children
Author(s) -
The ESCAPE Trial Group
Publication year - 2009
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0902066
Subject(s) - medicine , blood pressure , renin–angiotensin system , chronic renal failure , kidney , kidney disease , cardiology , urology , endocrinology
Although inhibition of the renin-angiotensin system delays the progression of renal failure in adults with chronic kidney disease, the blood-pressure target for optimal renal protection is controversial. We assessed the long-term renoprotective effect of intensified blood-pressure control among children who were receiving a fixed high dose of an angiotensin-converting-enzyme (ACE) inhibitor.
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