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A Randomized Trial of Rosuvastatin in the Prevention of Venous Thromboembolism
Author(s) -
Robert J. Glynn,
Eleanor Danielson,
Francisco Antônio Helfenstein Fonseca,
Jacques Genest,
Antonio M. Gotto,
John J.P. Kastelein,
Wolfgang Köenig,
Peter Libby,
Alberto J. Lorenzatti,
Jean MacFadyen,
Børge G. Nordestgaard,
James Shepherd,
James T. Willerson,
Paul M. Ridker
Publication year - 2009
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0900241
Subject(s) - medicine , rosuvastatin , randomized controlled trial , observational study , venous thrombosis , intensive care medicine , venous thromboembolism , statin , cardiology , thrombosis
Controversy persists regarding the extent of shared pathways between arterial and venous thrombosis and whether treatments of known efficacy for one disease process have consistent benefits for the other. Observational studies have yielded variable estimates of the effect of statin therapy on the risk of venous thromboembolism, and evidence from randomized trials is lacking.

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