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Chlorhexidine–Alcohol versus Povidone–Iodine for Surgical-Site Antisepsis
Author(s) -
Rabih O. Darouiche,
Matthew J. Wall,
Kamal M.F. Itani,
Mary F. Otterson,
Alexandra L. Webb,
Matthew M. Carrick,
Harold J. Miller,
Samir S. Awad,
Cynthia T. Crosby,
Michael Mosier,
Atef AlSharif,
David H. Berger
Publication year - 2010
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0810988
Subject(s) - medicine , chlorhexidine , iodine , surgery , alcohol , confidence interval , antiseptic , surgical site infection , chlorhexidine gluconate , adverse effect , anesthesia , dentistry , pathology , biochemistry , chemistry , materials science , metallurgy
Since the patient's skin is a major source of pathogens that cause surgical-site infection, optimization of preoperative skin antisepsis may decrease postoperative infections. We hypothesized that preoperative skin cleansing with chlorhexidine-alcohol is more protective against infection than is povidone-iodine.

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