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Rates of Serious Infection after Changes in Regimens for Medical Abortion
Author(s) -
Mary Fjerstad,
James Trussell,
Irving Sivin,
E. Steve Lichtenberg,
Vanessa Cullins
Publication year - 2009
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0809146
Subject(s) - misoprostol , medicine , medical abortion , mifepristone , abortion , obstetrics , regimen , pregnancy , chlamydia , family planning , gynecology , population , research methodology , genetics , immunology , biology , environmental health
From 2001 through March 2006, Planned Parenthood health centers throughout the United States provided medical abortion (abortion by means of medication) principally by a regimen of oral mifepristone followed 24 to 48 hours later by vaginal misoprostol. In response to concern about serious infections, in early 2006 Planned Parenthood changed the route of misoprostol administration from vaginal to buccal and required either routine provision of antibiotics or universal screening and treatment for chlamydia; in July 2007, Planned Parenthood began requiring routine treatment with antibiotics for all medical abortions.

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