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Artemisinin Resistance inPlasmodium falciparumMalaria
Author(s) -
Arjen M. Dondorp,
François Nosten,
Poravuth Yi,
Debashish Das,
Aung Pyae Phyo,
Joel Tärning,
Khin Maung Lwin,
Frédéric Ariey,
Warunee Hanpithakpong,
Sue J. Lee,
Pascal Ringwald,
Kamolrat Silamut,
Mallika Imwong,
Kesinee Chotivanich,
Pharath Lim,
Trent Herdman,
Sen Sam An,
Shunmay Yeung,
Pratap Singhasiva,
Nicholas Day,
Niklas Lindegårdh,
Duong Socheat,
Nicholas J. White
Publication year - 2009
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0808859
Subject(s) - artesunate , mefloquine , artemisinin , plasmodium falciparum , medicine , dihydroartemisinin , malaria , pharmacology , pharmacokinetics , interquartile range , drug resistance , immunology , biology , microbiology and biotechnology
Artemisinin-based combination therapies are the recommended first-line treatments of falciparum malaria in all countries with endemic disease. There are recent concerns that the efficacy of such therapies has declined on the Thai-Cambodian border, historically a site of emerging antimalarial-drug resistance.

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