Percent Emphysema, Airflow Obstruction, and Impaired Left Ventricular Filling | Zendy

R. Graham Barr | Zendy; David A. Bluemke | Zendy; Firas S. Ahmed | Zendy; J. Jeffrey Carr | Zendy; Paul Enright | Zendy; Eric A. Hoffman | Zendy; Rui Jiang | Zendy; Steven M. Kawut | Zendy; Richard A. Kronmal | Zendy; João A.C. Lima | Zendy; Eyal Shahar | Zendy; Lewis J. Smith | Zendy; Karol E. Watson | Zendy

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Percent Emphysema, Airflow Obstruction, and Impaired Left Ventricular Filling

Author(s) -

R. Graham Barr,

David A. Bluemke,

Firas S. Ahmed,

J. Jeffrey Carr,

Paul Enright,

Eric A. Hoffman,

Rui Jiang,

Steven M. Kawut,

Richard A. Kronmal,

João A.C. Lima,

Eyal Shahar,

Lewis J. Smith,

Karol E. Watson

Publication year - 2010

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0808836

Subject(s) - medicine , cardiology , spirometry , stroke volume , obstructive lung disease , lung volumes , confidence interval , ejection fraction , lung , copd , heart failure , asthma

Very severe chronic obstructive pulmonary disease causes cor pulmonale with elevated pulmonary vascular resistance and secondary reductions in left ventricular filling, stroke volume, and cardiac output. We hypothesized that emphysema, as detected on computed tomography (CT), and airflow obstruction are inversely related to left ventricular end-diastolic volume, stroke volume, and cardiac output among persons without very severe lung disease.

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