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Irbesartan in Patients with Heart Failure and Preserved Ejection Fraction
Author(s) -
Barry M. Massie,
Peter E. Carson,
John J.V. McMurray,
Michel Komajda,
Robert S. McKelvie,
Michael R. Zile,
Susan Anderson,
Mark Donovan,
Erik Iverson,
C Staiger,
Agata Ptaszynska
Publication year - 2008
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0805450
Subject(s) - irbesartan , medicine , hazard ratio , heart failure , ejection fraction , cardiology , myocardial infarction , angina , stroke (engine) , placebo , confidence interval , blood pressure , mechanical engineering , alternative medicine , pathology , engineering
Approximately 50% of patients with heart failure have a left ventricular ejection fraction of at least 45%, but no therapies have been shown to improve the outcome of these patients. Therefore, we studied the effects of irbesartan in patients with this syndrome.

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