Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma | Zendy

Yujin Hoshida | Zendy; Augusto Villanueva | Zendy; Masahiro Kobayashi | Zendy; Judit Peix | Zendy; Derek Y. Chiang | Zendy; Amy L. Camargo | Zendy; Supriya Gupta | Zendy; Jamie Moore | Zendy; Matthew J. Wrobel | Zendy; Jim Lerner | Zendy; Michael Reich | Zendy; Jennifer A. Chan | Zendy; Jonathan N. Glickman | Zendy; Kenji Ikeda | Zendy; Masaji Hashimoto | Zendy; Goro Watanabe | Zendy; Maria Grazia Daidone | Zendy; Sasan Roayaie | Zendy; Myron Schwartz | Zendy; Swan N. Thung | Zendy; Helga B. Salvesen | Zendy; Stacey Gabriel | Zendy; Vincenzo Mazzaferro | Zendy; Jordi Bruix | Zendy; Scott L. Friedman | Zendy; Hiromitsu Kumada | Zendy; Josep M. Llovet | Zendy; Todd R. Golub | Zendy

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Gene Expression in Fixed Tissues and Outcome in Hepatocellular Carcinoma

Author(s) -

Yujin Hoshida,

Augusto Villanueva,

Masahiro Kobayashi,

Judit Peix,

Derek Y. Chiang,

Amy L. Camargo,

Supriya Gupta,

Jamie Moore,

Matthew J. Wrobel,

Jim Lerner,

Michael Reich,

Jennifer A. Chan,

Jonathan N. Glickman,

Kenji Ikeda,

Masaji Hashimoto,

Goro Watanabe,

Maria Grazia Daidone,

Sasan Roayaie,

Myron Schwartz,

Swan N. Thung,

Helga B. Salvesen,

Stacey Gabriel,

Vincenzo Mazzaferro,

Jordi Bruix,

Scott L. Friedman,

Hiromitsu Kumada,

Josep M. Llovet,

Todd R. Golub

Publication year - 2008

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0804525

Subject(s) - hepatocellular carcinoma , medicine , gene expression profiling , gene signature , gene expression , carcinoma , gene , phenotype , oncology , pathology , cancer research , biology , genetics

It is a challenge to identify patients who, after undergoing potentially curative treatment for hepatocellular carcinoma, are at greatest risk for recurrence. Such high-risk patients could receive novel interventional measures. An obstacle to the development of genome-based predictors of outcome in patients with hepatocellular carcinoma has been the lack of a means to carry out genomewide expression profiling of fixed, as opposed to frozen, tissue.

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