Effects of Intensive Glucose Lowering in Type 2 Diabetes
Author(s) -
Hertzel C. Gerstein,
Michael E. Miller,
Robert P. Byington,
David C. Goff,
J. Thomas Bigger,
John B. Buse,
William C. Cushman,
Saul Genuth,
Faramarz IsmailBeigi,
Richard H. Grimm,
Jeffrey L. Probstfield,
Denise G. SimonsMorton,
William T. Friedewald
Publication year - 2008
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0802743
Subject(s) - medicine , glycated hemoglobin , hazard ratio , type 2 diabetes , confidence interval , discontinuation , diabetes mellitus , myocardial infarction , randomized controlled trial , endocrinology
Epidemiologic studies have shown a relationship between glycated hemoglobin levels and cardiovascular events in patients with type 2 diabetes. We investigated whether intensive therapy to target normal glycated hemoglobin levels would reduce cardiovascular events in patients with type 2 diabetes who had either established cardiovascular disease or additional cardiovascular risk factors.
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