Toll-like Receptor 4 Polymorphisms and Aspergillosis in Stem-Cell Transplantation | Zendy

PierreYves Bochud | Zendy; Jason W. Chien | Zendy; Kieren A. Marr | Zendy; Wendy M. Leisenring | Zendy; Arlo Upton | Zendy; Marta Janer | Zendy; Stéphanie Rodrigues | Zendy; Sarah Li | Zendy; John A. Hansen | Zendy; Lue Ping Zhao | Zendy; Alan Aderem | Zendy; Michael Boeckh | Zendy

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Toll-like Receptor 4 Polymorphisms and Aspergillosis in Stem-Cell Transplantation

Author(s) -

PierreYves Bochud,

Jason W. Chien,

Kieren A. Marr,

Wendy M. Leisenring,

Arlo Upton,

Marta Janer,

Stéphanie Rodrigues,

Sarah Li,

John A. Hansen,

Lue Ping Zhao,

Alan Aderem,

Michael Boeckh

Publication year - 2008

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa0802629

Subject(s) - aspergillosis , odds ratio , hematopoietic stem cell transplantation , hazard ratio , immunology , single nucleotide polymorphism , medicine , transplantation , haplotype , oncology , biology , genotype , confidence interval , genetics , gene

Toll-like receptors (TLRs) are essential components of the immune response to fungal pathogens. We examined the role of TLR polymorphisms in conferring a risk of invasive aspergillosis among recipients of allogeneic hematopoietic-cell transplants.

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