Male Circumcision for the Prevention of HSV-2 and HPV Infections and Syphilis
Author(s) -
Aaron A.R. Tobian,
David Serwadda,
Thomas C. Quinn,
Godfrey Kigozi,
Patti E. Gravitt,
Oliver Laeyendecker,
Blake Charvat,
Victor Ssempijja,
Melissa Riedesel,
Amy E. Oliver,
Rebecca G. Nowak,
Lawrence H. Moulton,
Michael Z. Chen,
Steven J. Reynolds,
Maria J. Wawer,
Ronald H. Gray
Publication year - 2009
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0802556
Subject(s) - medicine , syphilis , seroconversion , hazard ratio , incidence (geometry) , sexually transmitted disease , confidence interval , randomized controlled trial , young adult , herpes simplex virus , immunology , obstetrics , human immunodeficiency virus (hiv) , virus , physics , optics
Male circumcision significantly reduced the incidence of human immunodeficiency virus (HIV) infection among men in three clinical trials. We assessed the efficacy of male circumcision for the prevention of herpes simplex virus type 2 (HSV-2) and human papillomavirus (HPV) infections and syphilis in HIV-negative adolescent boys and men.
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