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Effect of Aspirin or Resistant Starch on Colorectal Neoplasia in the Lynch Syndrome
Author(s) -
John Burn,
D. Timothy Bishop,
JukkaPekka Mecklin,
Finlay Macrae,
Gabriela Möslein,
Sylviane Olschwang,
Marie-Luise Bisgaard,
Raj Ramesar,
Diana Eccles,
Eamonn R. Maher,
Lucio Bertario,
Heikki Järvinen,
Annika Lindblom,
D. Gareth Evans,
Jan Lubiński,
Patrick J. Morrison,
Judy W.C. Ho,
Hans F. A. Vasen,
Lucy Side,
Huw Thomas,
Rodney J. Scott,
Malcolm G. Dunlop,
G Barker,
Faye Elliott,
Jeremy R. Jass,
Riccardo Fodde,
Henry T. Lynch,
John C. Mathers
Publication year - 2008
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0801297
Subject(s) - aspirin , medicine , colorectal cancer , lynch syndrome , gastroenterology , observational study , resistant starch , oncology , cancer , dna mismatch repair , starch , food science , chemistry
Observational and epidemiologic data indicate that the use of aspirin reduces the risk of colorectal neoplasia; however, the effects of aspirin in the Lynch syndrome (hereditary nonpolyposis colon cancer) are not known. Resistant starch has been associated with an antineoplastic effect on the colon.

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