The Effects of Tibolone in Older Postmenopausal Women
Author(s) -
Steven R. Cummings,
Bruce Ettinger,
Pierre D. Delmas,
Peter Kenemans,
V. M. Stathopoulos,
Paul E. Verweij,
Mirjam Mol-Arts,
Lenus Kloosterboer,
Lori Mosca,
Claus Christiansen,
John Bilezikian,
Eduardo Kerzberg,
Susan R. Johnson,
José Zanchetta,
Diederich E. Grobbee,
Wilfried Seifert,
Richard Eastell
Publication year - 2008
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0800743
Subject(s) - tibolone , medicine , hazard ratio , osteoporosis , breast cancer , relative risk , placebo , confidence interval , surgery , cancer , menopause , pathology , alternative medicine
Tibolone has estrogenic, progestogenic, and androgenic effects. Although tibolone prevents bone loss, its effects on fractures, breast cancer, and cardiovascular disease are uncertain.
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