Shared Genetic Causes of Cardiac Hypertrophy in Children and Adults | Zendy

Hiroyuki Morita | Zendy; Heidi L. Rehm | Zendy; Andres Menesses | Zendy; Barbara McDonough | Zendy; Amy E. Roberts | Zendy; Raju Kucherlapati | Zendy; Jeffrey A. Towbin | Zendy; Jonathan G. Seidman | Zendy; Christine E. Seidman | Zendy

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Shared Genetic Causes of Cardiac Hypertrophy in Children and Adults

Author(s) -

Hiroyuki Morita,

Heidi L. Rehm,

Andres Menesses,

Barbara McDonough,

Amy E. Roberts,

Raju Kucherlapati,

Jeffrey A. Towbin,

Jonathan G. Seidman,

Christine E. Seidman

Publication year - 2008

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa075463

Subject(s) - myh7 , missense mutation , hypertrophic cardiomyopathy , medicine , cardiomyopathy , mutation , gene mutation , muscle hypertrophy , left ventricular hypertrophy , genetics , cardiology , gene , heart failure , biology , blood pressure , gene isoform

The childhood onset of idiopathic cardiac hypertrophy that occurs without a family history of cardiomyopathy can portend a poor prognosis. Despite morphologic similarities to genetic cardiomyopathies of adulthood, the contribution of genetics to childhood-onset hypertrophy is unknown.

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