TP53Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck | Zendy

Maria Luana Poeta | Zendy; Judith Manola | Zendy; Meredith A. Goldwasser | Zendy; Arlene A. Forastiere | Zendy; Nicole Benoit | Zendy; Joseph A. Califano | Zendy; John A. Ridge | Zendy; Jarrard Goodwin | Zendy; Daniel E. Kenady | Zendy; John R. Saunders | Zendy; William H. Westra | Zendy; David Sidransky | Zendy; Wayne M. Koch | Zendy

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TP53Mutations and Survival in Squamous-Cell Carcinoma of the Head and Neck

Author(s) -

Maria Luana Poeta,

Judith Manola,

Meredith A. Goldwasser,

Arlene A. Forastiere,

Nicole Benoit,

Joseph A. Califano,

John A. Ridge,

Jarrard Goodwin,

Daniel E. Kenady,

John R. Saunders,

William H. Westra,

David Sidransky,

Wayne M. Koch

Publication year - 2007

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa073770

Subject(s) - hazard ratio , medicine , mutation , confidence interval , head and neck cancer , head and neck squamous cell carcinoma , carcinoma , oncology , cancer , pathology , cancer research , gene , gastroenterology , genetics , biology

The abrogation of function of the tumor-suppressor protein p53 as a result of mutation of its gene, TP53, is one of the most common genetic alterations in cancer cells. We evaluated TP53 mutations and survival in patients with squamous-cell carcinoma of the head and neck.

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