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Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon
Author(s) -
Adrian M. Di Bisceglie,
Mitchell L. Shiffman,
Gregory T. Everson,
Karen L. Lindsay,
James E. Everhart,
Elizabeth C. Wright,
William M. Lee,
Anna S. Lok,
Herbert L. Bonkovsky,
Timothy R. Morgan,
Marc G. Ghany,
Chihiro Morishima,
Kristin K. Snow,
Jules L. Dienstag
Publication year - 2008
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa0707615
Subject(s) - medicine , hepatocellular carcinoma , cirrhosis , antiviral therapy , gastroenterology , chronic hepatitis , hepatitis c , liver disease , chronic liver disease , disease , immunology , virus
In patients with chronic hepatitis C who do not have a response to antiviral treatment, the disease may progress to cirrhosis, liver failure, hepatocellular carcinoma, and death. Whether long-term antiviral therapy can prevent progressive liver disease in such patients remains uncertain.

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