Natural History and Outcome in Systemic AA Amyloidosis | Zendy

Helen J. Lachmann | Zendy; Hugh J. B. Goodman | Zendy; Janet A. Gilbertson | Zendy; J. Ruth Gallimore | Zendy; Caroline Sabin | Zendy; Julian D. Gillmore | Zendy; Philip N. Hawkins | Zendy

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Natural History and Outcome in Systemic AA Amyloidosis

Author(s) -

Helen J. Lachmann,

Hugh J. B. Goodman,

Janet A. Gilbertson,

J. Ruth Gallimore,

Caroline Sabin,

Julian D. Gillmore,

Philip N. Hawkins

Publication year - 2007

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa070265

Subject(s) - amyloidosis , medicine , aa amyloidosis , amyloid (mycology) , serum amyloid a , serum amyloid a protein , natural history , complication , amyloid fibril , acute phase protein , systemic disease , al amyloidosis , pathology , gastroenterology , immunology , disease , inflammation , amyloid β , antibody , familial mediterranean fever , immunoglobulin light chain

Deposition of amyloid fibrils derived from circulating acute-phase reactant serum amyloid A protein (SAA) causes systemic AA amyloidosis, a serious complication of many chronic inflammatory disorders. Little is known about the natural history of AA amyloidosis or its response to treatment.

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