Donepezil for the Treatment of Agitation in Alzheimer's Disease
Author(s) -
Robert Howard,
Edmund Juszczak,
Clive Ballard,
Peter Bentham,
Richard G. Brown,
Roger Bullock,
Alistair Burns,
Clive Holmes,
Robin Jacoby,
Tony Johnson,
Martín Knapp,
James Lindesay,
John T. O’Brien,
Gordon Wilcock,
Cornelius Katona,
Roy Jones,
Julia DeCesare,
Michaela Rodger
Publication year - 2007
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa066583
Subject(s) - donepezil , placebo , medicine , clinical global impression , psychomotor agitation , alzheimer's disease , anesthesia , psychiatry , dementia , disease , alternative medicine , pathology
Agitation is a common and distressing symptom in patients with Alzheimer's disease. Cholinesterase inhibitors improve cognitive outcomes in such patients, but the benefits of these drugs for behavioral disturbances are unclear.
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