Transfusion Strategies for Patients in Pediatric Intensive Care Units
Author(s) -
Jacques Lacroix,
Paul C. Hébert,
James S. Hutchison,
Heather Hume,
Marisa Tucci,
Thiérry Ducruet,
France Gauvin,
JeanPaul Collet,
Baruch Toledano,
Pierre Robillard,
Ari R. Joffe,
Dominique Biarent,
Kathleen L. Meert,
Mark Peters
Publication year - 2007
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa066240
Subject(s) - medicine , intensive care medicine , critically ill , organ dysfunction , packed red blood cells , blood transfusion , intensive care , hemoglobin , surgery , sepsis
The optimal hemoglobin threshold for erythrocyte transfusions in critically ill children is unknown. We hypothesized that a restrictive transfusion strategy of using packed red cells that were leukocyte-reduced before storage would be as safe as a liberal transfusion strategy, as judged by the outcome of multiple-organ dysfunction.
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