Corticosteroids for Bacterial Meningitis in Adults in Sub-Saharan Africa
Author(s) -
Matthew Scarborough,
Stephen B. Gordon,
C. W. M. Whitty,
Neil French,
Yasin Njalale,
Alex Chitani,
Tim Peto,
David G. Lalloo,
Eduard E. Zijlstra
Publication year - 2007
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa065711
Subject(s) - medicine , ceftriaxone , placebo , odds ratio , meningitis , dexamethasone , context (archaeology) , randomized controlled trial , confidence interval , surgery , antibiotics , paleontology , biology , alternative medicine , pathology , microbiology and biotechnology
In sub-Saharan Africa, bacterial meningitis is common and is associated with a high mortality. Adjuvant therapy with corticosteroids reduces mortality among adults in the developed world, but it has not been adequately tested in developing countries or in the context of advanced human immunodeficiency virus (HIV) infection.
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