The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells | Zendy

Rui Liu | Zendy; Xinhao Wang | Zendy; Grace Chen | Zendy; Piero Dalerba | Zendy; Austin Gurney | Zendy; Timothy Hoey | Zendy; Gavin Sherlock | Zendy; John Lewicki | Zendy; Kerby Shedden | Zendy; Michael F. Clarke | Zendy

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The Prognostic Role of a Gene Signature from Tumorigenic Breast-Cancer Cells

Author(s) -

Rui Liu,

Xinhao Wang,

Grace Chen,

Piero Dalerba,

Austin Gurney,

Timothy Hoey,

Gavin Sherlock,

John Lewicki,

Kerby Shedden,

Michael F. Clarke

Publication year - 2007

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa063994

Subject(s) - breast cancer , medicine , oncology , metastasis , cd44 , gene signature , cancer , ca15 3 , survival rate , population , lung cancer , cancer research , cd24 , gene , gene expression , cell , biology , genetics , environmental health , biochemistry

Breast cancers contain a minority population of cancer cells characterized by CD44 expression but low or undetectable levels of CD24 (CD44+CD24-/low) that have higher tumorigenic capacity than other subtypes of cancer cells.

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