Class of Antiretroviral Drugs and the Risk of Myocardial Infarction
Author(s) -
Nina FriisMøller,
Peter Reiss,
Caroline Sabin,
Rainer Weber,
Antonella d’Arminio Monforte,
Wafaa ElSadr,
Rodolphe Thiébaut,
Stéphane De Wit,
Ole Kirk,
Éric Fontas,
Matthew Law,
Andrew Phillips,
Jens Lundgren
Publication year - 2007
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa062744
Subject(s) - myocardial infarction , medicine , relative risk , incidence (geometry) , protease , confidence interval , reverse transcriptase inhibitor , infarction , prospective cohort study , cardiology , viral load , immunology , human immunodeficiency virus (hiv) , antiretroviral therapy , enzyme , biology , biochemistry , physics , optics
We have previously demonstrated an association between combination antiretroviral therapy and the risk of myocardial infarction. It is not clear whether this association differs according to the class of antiretroviral drugs. We conducted a study to investigate the association of cumulative exposure to protease inhibitors and nonnucleoside reverse-transcriptase inhibitors with the risk of myocardial infarction.
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