Bivalirudin for Patients with Acute Coronary Syndromes
Author(s) -
Gregg W. Stone,
Brent McLaurin,
David A. Cox,
Michel E. Bertrand,
A. Michael Lincoff,
Jeffrey W. Moses,
Harvey D. White,
Stuart J. Pocock,
James H. Ware,
Frederick Feit,
Antonio Colombo,
Philip E. Aylward,
Ángel Cequier,
Harald Darius,
Walter Desmet,
Ramin Ebrahimi,
Martial Hamon,
Lars Hvilsted Rasmussen,
H. J. Rupprecht,
James W. Hoekstra,
Roxana Mehran,
E. Magnus Ohman
Publication year - 2006
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa062437
Subject(s) - medicine , bivalirudin , cardiology , acute coronary syndrome , percutaneous coronary intervention , myocardial infarction
Current guidelines for patients with moderate- or high-risk acute coronary syndromes recommend an early invasive approach with concomitant antithrombotic therapy, including aspirin, clopidogrel, unfractionated or low-molecular-weight heparin, and glycoprotein IIb/IIIa inhibitors. We evaluated the role of thrombin-specific anticoagulation with bivalirudin in such patients.
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