International Trial of the Edmonton Protocol for Islet Transplantation
Author(s) -
A. M. James Shapiro,
Camillo Ricordi,
Bernhard J. Hering,
Hugh Auchincloss,
Robert Lindblad,
R. Paul Robertson,
Antonio Secchi,
Mathias D. Brendel,
Thierry Berney,
Daniel C. Brennan,
Enrico Cagliero,
Rodolfo Alejandro,
Edmond A. Ryan,
Barbara DiMercurio,
Philippe Morel,
Kenneth S. Polonsky,
Jo-Anna Reems,
Reinhard G. Bretzel,
Federico Bertuzzi,
Tatiana Froud,
Raja Kandaswamy,
David E.R. Sutherland,
George S. Eisenbarth,
Miriam Segal,
Jutta Preiksaitis,
Gregory S. Korbutt,
Franca B. Barton,
Lisa Viviano,
Vicki SeyfertMargolis,
Jeffrey A. Bluestone,
Jonathan R. T. Lakey
Publication year - 2006
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa061267
Subject(s) - medicine , transplantation , glycemic , islet , hypoglycemia , insulin , diabetes mellitus , clinical endpoint , glycated hemoglobin , islet cell transplantation , type 1 diabetes , type 2 diabetes mellitus , type 2 diabetes , randomized controlled trial , endocrinology
Islet transplantation offers the potential to improve glycemic control in a subgroup of patients with type 1 diabetes mellitus who are disabled by refractory hypoglycemia. We conducted an international, multicenter trial to explore the feasibility and reproducibility of islet transplantation with the use of a single common protocol (the Edmonton protocol).
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom