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Homocysteine Lowering with Folic Acid and B Vitamins in Vascular Disease
Author(s) -
Eva Lonn,
Salim Yusuf,
Malcolm J Arnold,
Patrick Sheridan,
Janice Pogue,
Mary Micks,
Matthew J McQueen,
Jeffrey L. Probstfield,
George Fodor,
Claes Held,
Jacques Genest
Publication year - 2006
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa060900
Subject(s) - medicine , placebo , relative risk , homocysteine , confidence interval , stroke (engine) , myocardial infarction , liter , vitamin b12 , vascular disease , diabetes mellitus , b vitamins , gastroenterology , surgery , endocrinology , pathology , mechanical engineering , engineering , alternative medicine
In observational studies, lower homocysteine levels are associated with lower rates of coronary heart disease and stroke. Folic acid and vitamins B6 and B12 lower homocysteine levels. We assessed whether supplementation reduced the risk of major cardiovascular events in patients with vascular disease.

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