Calcium plus Vitamin D Supplementation and the Risk of Colorectal Cancer
Author(s) -
Jean WactawskiWende,
Jane Morley Kotchen,
Garnet L. Anderson,
Annlouise R. Assaf,
Robert L. Brunner,
Mary Jo O’Sullivan,
Karen L. Margolis,
Judith K. Ockene,
Lawrence S. Phillips,
Linda M. Pottern,
Ross L. Prentice,
John A. Robbins,
Thomas E. Rohan,
Gloria E. Sarto,
Santosh Sharma,
Marcia L. Stefanick,
Linda Van Horn,
Robert B. Wallace,
Evelyn P Whitlock,
Tamsen Bassford,
Shirley A.A. Beresford,
Henry R. Black,
Denise E. Bonds,
Robert G. Brzyski,
Bette J. Caan,
Rowan T. Chlebowski,
Barbara Cochrane,
Cedric F. Garland,
Margery Gass,
Jennifer Hays,
Gerardo Heiss,
Susan L. Hendrix,
Barbara V. Howard,
Judith Hsia,
F. Allan Hubbell,
Rebecca D. Jackson,
Karen Johnson,
Howard Judd,
Charles Kooperberg,
Lewis H. Kuller,
Andrea Z. LaCroix,
Dorothy S. Lane,
Robert D. Langer,
Norman L. Lasser,
Cora E. Lewis,
Marian C. Limacher,
JoAnn E. Manson
Publication year - 2006
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa055222
Subject(s) - medicine , colorectal cancer , vitamin d and neurology , hazard ratio , placebo , calcium , gastroenterology , vitamin , randomized controlled trial , incidence (geometry) , cancer , confidence interval , pathology , physics , alternative medicine , optics
Higher intake of calcium and vitamin D has been associated with a reduced risk of colorectal cancer in epidemiologic studies and polyp recurrence in polyp-prevention trials. However, randomized-trial evidence that calcium with vitamin D supplementation is beneficial in the primary prevention of colorectal cancer is lacking.
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