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Dronedarone for Maintenance of Sinus Rhythm in Atrial Fibrillation or Flutter
Author(s) -
Bramah N. Singh,
Stuart J. Connolly,
Harry J.G.M. Crijns,
DenisClaude Roy,
Peter R. Kowey,
Alessandro Capucci,
David Radzik,
Etienne Aliot,
Stefan H. Hohnloser
Publication year - 2007
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa054686
Subject(s) - dronedarone , medicine , amiodarone , atrial fibrillation , atrial flutter , sinus rhythm , placebo , cardiology , antiarrhythmic agent , randomized controlled trial , clinical endpoint , anesthesia , heart disease , alternative medicine , pathology
Amiodarone is effective in maintaining sinus rhythm in atrial fibrillation but is associated with potentially serious toxic effects. Dronedarone is a new antiarrhythmic agent pharmacologically related to amiodarone but developed to reduce the risk of side effects.

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