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AMG 531, a Thrombopoiesis-Stimulating Protein, for Chronic ITP
Author(s) -
James B. Bussel,
David J. Kuter,
James N. George,
Robert McMillan,
Louis M. Aledort,
George T. Conklin,
Alan Lichtin,
Roger M. Lyons,
Jorge J. Nieva,
Jeffrey S. Wasser,
Israel Wiznitzer,
Reggie Kelly,
Chien-Feng Chen,
Janet L. Nichol
Publication year - 2006
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa054626
Subject(s) - medicine , thrombopoiesis , platelet , thrombocytopenic purpura , adverse effect , placebo , gastroenterology , surgery , megakaryocyte , pathology , stem cell , haematopoiesis , biology , genetics , alternative medicine
Most current treatments for chronic immune thrombocytopenic purpura (ITP) act by decreasing platelet destruction. In a phase 1-2 study, we administered a thrombopoiesis-stimulating protein, AMG 531, to patients with ITP.

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