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Effectiveness of Antipsychotic Drugs in Patients with Chronic Schizophrenia
Author(s) -
Jeffrey A. Lieberman,
T. Scott Stroup,
Joseph P. McEvoy,
Marvin S. Swartz,
Robert A. Rosenheck,
Diana O. Perkins,
Richard S.E. Keefe,
Sonia M. Davis,
C.E. Davis,
Barry D. Lebowitz,
Joanne B. Severe,
John Hsiao
Publication year - 2005
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa051688
Subject(s) - ziprasidone , quetiapine , olanzapine , risperidone , perphenazine , medicine , discontinuation , antipsychotic , atypical antipsychotic , clozapine , schizophrenia (object oriented programming) , psychiatry , anesthesia , pharmacology
The relative effectiveness of second-generation (atypical) antipsychotic drugs as compared with that of older agents has been incompletely addressed, though newer agents are currently used far more commonly. We compared a first-generation antipsychotic, perphenazine, with several newer drugs in a double-blind study.

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