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Single-Dose Azithromycin versus Penicillin G Benzathine for the Treatment of Early Syphilis
Author(s) -
Gabriele Riedner,
Mary Rusizoka,
Jim Todd,
Leonard Maboko,
Michael Höelscher,
Donan Mmbando,
Eleuter Samky,
Eligius Lyamuya,
David Mabey,
Heiner Grosskurth,
Richard Hayes
Publication year - 2005
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa044284
Subject(s) - medicine , azithromycin , rapid plasma reagin , confidence interval , syphilis , penicillin , primary syphilis , surgery , antibiotics , immunology , human immunodeficiency virus (hiv) , treponema , microbiology and biotechnology , biology
Pilot studies suggest that a single, 2-g oral dose of azithromycin may be an alternative to a 2.4-MU intramuscular dose of penicillin G benzathine in the prevention and treatment of syphilis. We evaluated the efficacy of treatment with azithromycin in a developing country.

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