Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma | Zendy

Roger Stupp | Zendy; Warren Mason | Zendy; Martin J. van den Bent | Zendy; Michael Weller | Zendy; Barbara Fisher | Zendy; Martin Taphoorn | Zendy; Karl Bélanger | Zendy; Alba A. Brandes | Zendy; Christine Marosi | Zendy; Ulrich Bogdahn | Zendy; Jürgen Curschmann | Zendy; Robert C. Janzer | Zendy; Samuel K. Ludwin | Zendy; Thierry Gorlia | Zendy; Anouk Allgeier | Zendy; Denis Lacombe | Zendy; J. Gregory Cairncross | Zendy; Elizabeth A. Eisenhauer | Zendy; R.O. Mirimanoff | Zendy

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Radiotherapy plus Concomitant and Adjuvant Temozolomide for Glioblastoma

Author(s) -

Roger Stupp,

Warren Mason,

Martin J. van den Bent,

Michael Weller,

Barbara Fisher,

Martin Taphoorn,

Karl Bélanger,

Alba A. Brandes,

Christine Marosi,

Ulrich Bogdahn,

Jürgen Curschmann,

Robert C. Janzer,

Samuel K. Ludwin,

Thierry Gorlia,

Anouk Allgeier,

Denis Lacombe,

J. Gregory Cairncross,

Elizabeth A. Eisenhauer,

R.O. Mirimanoff

Publication year - 2005

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa043330

Subject(s) - temozolomide , medicine , radiation therapy , concomitant , glioblastoma , adjuvant , adjuvant radiotherapy , oncology , surgery , cancer research

Glioblastoma, the most common primary brain tumor in adults, is usually rapidly fatal. The current standard of care for newly diagnosed glioblastoma is surgical resection to the extent feasible, followed by adjuvant radiotherapy. In this trial we compared radiotherapy alone with radiotherapy plus temozolomide, given concomitantly with and after radiotherapy, in terms of efficacy and safety.

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