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Comparison of Low-Intensity Warfarin Therapy with Conventional-Intensity Warfarin Therapy for Long-Term Prevention of Recurrent Venous Thromboembolism
Author(s) -
Clive Kearon,
Jeffrey S. Ginsberg,
Michael J. Kovacs,
David R. Anderson,
Philip Wells,
Jim A. Julian,
Betsy MacKin,
Jeffrey I. Weitz,
Mark Crowther,
Sean Dolan,
Alexander G.G. Turpie,
William Geerts,
Susan Solymoss,
Paul Nguyen,
Christine Demers,
Susan R. Kahn,
Jeannine Kassis,
Marc Rodger,
Julie Hambleton,
Michael Gent
Publication year - 2003
Publication title -
new england journal of medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 19.889
H-Index - 1030
eISSN - 1533-4406
pISSN - 0028-4793
DOI - 10.1056/nejmoa035422
Subject(s) - medicine , warfarin , venous thromboembolism , anticoagulant therapy , anticoagulant , major bleeding , surgery , atrial fibrillation , thrombosis
Warfarin is very effective in preventing recurrent venous thromboembolism but is also associated with a substantial risk of bleeding. After three months of conventional warfarin therapy, a lower dose of anticoagulant medication may result in less bleeding and still prevent recurrent venous thromboembolism.

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