Prognostic Value of Myeloperoxidase in Patients with Chest Pain | Zendy

MarieLuise Brennan | Zendy; Marc S. Penn | Zendy; Frederick Van Lente | Zendy; Vijay Nambi | Zendy; Mehdi H. Shishehbor | Zendy; Ronnier J. Aviles | Zendy; Marlene Goormastic | Zendy; Michael Pepoy | Zendy; Ellen McErlean | Zendy; Eric J. Topol | Zendy; Steven E. Nissen | Zendy; Stanley L. Hazen | Zendy

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Prognostic Value of Myeloperoxidase in Patients with Chest Pain

Author(s) -

MarieLuise Brennan,

Marc S. Penn,

Frederick Van Lente,

Vijay Nambi,

Mehdi H. Shishehbor,

Ronnier J. Aviles,

Marlene Goormastic,

Michael Pepoy,

Ellen McErlean,

Eric J. Topol,

Steven E. Nissen,

Stanley L. Hazen

Publication year - 2003

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa035003

Subject(s) - medicine , myeloperoxidase , myocardial infarction , chest pain , confidence interval , odds ratio , cardiology , unstable angina , culprit , troponin t , coronary artery disease , troponin , inflammation

Inflammation is linked to adverse outcomes in acute coronary syndromes. Myeloperoxidase, an abundant leukocyte enzyme, is elevated in culprit lesions that have fissured or ruptured in patients with sudden death from cardiac causes. Numerous lines of evidence suggest mechanistic links between myeloperoxidase and both inflammation and cardiovascular disease.

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