Endoscopic Laser Surgery versus Serial Amnioreduction for Severe Twin-to-Twin Transfusion Syndrome | Zendy

MarieVictoire Sénat | Zendy; Jan Deprest | Zendy; Michel Boulvain | Zendy; A Paupe | Zendy; Norbert Winer | Zendy; Y. Ville | Zendy

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Endoscopic Laser Surgery versus Serial Amnioreduction for Severe Twin-to-Twin Transfusion Syndrome

Author(s) -

MarieVictoire Sénat,

Jan Deprest,

Michel Boulvain,

A Paupe,

Norbert Winer,

Y. Ville

Publication year - 2004

Publication title -

new england journal of medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 19.889

H-Index - 1030

eISSN - 1533-4406

pISSN - 0028-4793

DOI - 10.1056/nejmoa032597

Subject(s) - medicine , interim analysis , twin to twin transfusion syndrome , laser coagulation , randomized controlled trial , laser surgery , surgery , gestational age , confidence interval , obstetrics , amniotic fluid , relative risk , incidence (geometry) , gestation , pregnancy , fetus , laser , physics , visual acuity , biology , optics , genetics

Monochorionic twin pregnancies complicated by severe twin-to-twin transfusion syndrome at midgestation can be treated by either serial amnioreduction (removal of large volumes of amniotic fluid) or selective fetoscopic laser coagulation of the communicating vessels on the chorionic plate. We conducted a randomized trial to compare the efficacy and safety of these two treatments.

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